Determining whether a research risk meets or exceeds a regulatory standard of risk acceptability is difficult. Recently a framework called the systematic evaluation of research risks (SERR) has been proposed as a method of comparing research risks with predetermined standards of acceptability. SERR purports to offer a systematic and largely determinate (definite) way to compare risks and say whether a specific research risk falls below or above an acknowledged standard of acceptable risk. Here the authors review some philosophical problems with (...) this framework, which they take to be representative of determinate approaches to risk comparison, and conclude that it should not be used in a stand-alone or determinate fashion. Instead, the authors suggest that a deliberative approach may be a more viable candidate for future development. Such an approach could be informed by methods such as SERR without being rigidly bound to them. (shrink)

BackgroundThe return of genetics and genomics research results has been a subject of ongoing global debate. Such feedback is ethically desirable to update participants on research findings particularly those deemed clinically significant. Although there is limited literature, debate continues in African on what constitutes appropriate practice regarding the return of results for genetics and genomics research. This study explored perspectives and ethical considerations of Ugandan genomics researchers regarding the return of genetics and genomics research results.MethodsThis was a qualitative study that (...) employed in-depth interviews. Thirty participants were purposively selected based on their expertise as genomics researchers in Uganda. Data were analysed through content analysis along the main themes of the study using a comprehensive thematic matrix, to identify common patterns arising from the narratives. NVivo software 12 was used to support data analysis.ResultsThe return of genetics and genomics research results was generally acceptable to researchers, and some indicated that they had previously returned individual or aggregate results to participants and communities. The main reasons cited for sharing research results with participants included their clinical utility, actionability and overall benefit to society. Ethical considerations for appropriate return of results included a need for effective community engagement, genetic counselling prior to disclosure of the results, adequate informed consent, and proper assessment of the implications of, or consequences of returning of results. However, the approaches to return of results were perceived as unstandardized due to the lack of appropriate regulatory frameworks.ConclusionsThe return of genetic and genomic research results is generally acceptable to researchers despite the lack of appropriate regulatory frameworks. Ethical considerations for return of genetics and genomics research results are highly divergent, hence the need for national ethical guidelines to appropriately regulate the practice. (shrink)

The problem of reference is central to the fields of linguistics, cognitive science, and epistemology yet it remains largely unresolved. Naming and Reference explains the reference of lexical terms, with particular emphasis placed on proper names, demonstrative pronouns and personal pronouns. It examines such specific issues as: how to account for the reference of names that are empty or speculative, which abound in science and philosophy, and how to account for intentional reference as in "he took Mary to be Jane." (...) Naming and Reference begins with a survey of the history of the subject within a philosophical and critical setting, from Locke, Brentano, Peirce, Frege, Russell, Strawson, Tarski, Carnap and Quine up to Kripke and Fodor. The rest of the book is devoted to an algorithmic theory of reference derived from Peirce's idea that signification is a three-way relationship involving a term, an object and an interpretant. The theory rounds out the causal notion of reference, while at the same time preserving Frege's distinction between sense and reference, and making a place for indexical terms. Through the use of various computer models, R. J. Nelson explores the meaning and reference of words to objects and the relationship of these phenomena to perception, belief and truth. The models used are parallel, connectionist computational models rather than the sequential models of mid-century artificial intelligence. The aim, in opposition to nativist and mental representation theories, is to account for the genesis of semantically interpretable symbols, not to assume them. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:The Authorship of the Abstract Revisited John 0. Nelson More than a dozen years ago, in the pages of The Philosophical Quarterly,1 this writer contested Sraffa and Keynes' claim, advanced in the introduction to their edition ofthe Abstract? that it was Hume and not Adam Smith (as traditionally supposed) who was the author of that work. The traditional view, which might be called the Adam Smith authorship-theory, (...) was largely inspired by and seemed nailed shut by Hume's reference to a "Mr Smith" in a letter to Francis Hutcheson, datedMarch 4, 1740.3There appeared tobe goodreasonsforidentifying this "Mr Smith" with Adam Smith and then the latter with the undivulged author of the Abstract. It was known, for instance, that previous to March 4, 1740, Adam Smith had been a student of Hutcheson's and that Hutcheson was in the habit of setting his students the task of writing abstracts of newly published philosophical works.4 Since Hutcheson had originallylooked with favor on both the Treatise and its author,5 it had to seem more than likely that he had set his students the task ofwriting an abstract ofthe newly published Treatise ofHume. It was known, too, that Adam Smith was in possession of a copy ofthe Treatise soon after the date of H.6 Who, then, might be the "Mr Smith" adverted to in H's "My Bookseller has sent to Mr Smith a Copy of my Book, which I hope he has receive, as well as your Letter," except that same student of Hutcheson's, Adam Smith? What other Smith might have been known to Hutcheson, whom Hume could have wanted to refer to? No other Smith appeared to fit the bill. But why should Hume have wanted to refer in his correspondence with Hutcheson to an obscure, sixteen-year-old student ofHutcheson's, besides going to the trouble of having his bookseller send him a copy of the Treatise, unless that student had in some way made himselfnot only known to Hume but so highly regarded that Hume would want to favor him, presumably at his own expense, with a copy ofthe Treatise? The only tenable answer had to seem to be that this same student had composed such a perceptive and laudatory précis of the Treatise for Hutcheson that the latter had shown it to Hume and Hume, in the honest attempt to excite interest and sales of that languishing work, had seen to its publication as the Abstractl These are the reasonings Volume XVII Number 1 83 JOHN O. NELSON and considerations that inspired and seemed to confirm the Adam Smith authorship-theory.7 As can be perceived, these reasonings and considerations all revolve around the reference to a "Mr Smith"in H andthe identification of that Smith with Adam Smith. When, therefore, Sraffa and Keynes in the introduction to their edition oftheAbstract pointed out that there existed another Smith who might arguably be the Mr Smith referred toin H, namely, the DubUn publisher oftwo ofHutcheson's works, John Smith "at the Philosopher's Head on the Blind Quay," its major prop being seemingly knocked out from under it, the Adam Smith authorship-theory crashed—at least in the eyes of the general world—to the ground. And in thelatter's place, various ofits supporting reasons being given a lease on life, such as Hume's well-known endeavors and desires to excite interest in this first work of his, the Hume authorship-theory, so to speak, seated itself. In my previous venture into this subject, "Has the Authorship of An Abstract ofa Treatise ofHuman Nature Really Been Decided?"8 I tried, I believe with some success, to show that Sraffa and Keynes' arguments were not so unanswerable as they were generally taken to be and that, in fact, they presented various difficulties which the traditional theory avoided. But what then occasions this new excursion into these troubled waters? What more is to be said that I did not say in "Decided"? In "Decided" I presented various arguments and considerations that showed that it was unlikely either that Hume was the author of theAbstract or that the Mr Smith referred to in H... (shrink)

My final aim in this paper is to show that Descartes is not guilty, as is so often maintained, of circular argumentation in the Meditations. But first it is important to uncover and remove certain tenacious misconceptions and confusions concerning what goes on in the Meditations which lend credence to the charge of circular argumentation. In this connection Mr. Harry Frankfurt's recent article, “Memory and the Cartesian Circle,” is peculiarly instructive; for it presents not only a completely untenable defence of (...) Descartes but one that, implicitly at least, rests on the very misconceptions that give substance to the notion of a Cartesian Circle. With the intention, then, of clearing the ground for the construction of my own defence of Descartes, I shall spend the first part of this paper examining Frankfurt's central thesis, the errors contained in it, and their sources. This thesis is contained in his statement, which I shall henceforth designate by the letter “J,” “Descartes did not attempt to justify present clear and distinct perceptions.”. (shrink)

Pierre Trémaux’s 1865 ideas on speciation have been unjustly derided following his acceptance by Marx and rejection by Engels, and almost nobody has read his ideas in a charitable light. Here we offer an interpretation based on translating the term sol as “habitat”, in order to show that Trémaux proposed a theory of allopatric speciation before Wagner and a punctuated equilibrium theory before Gould and Eldredge, and translate the relevant discussion from the French. We believe he may have influenced Darwin’s (...) revision to the third edition of the Origin on rates of evolution, and suggest that Gould’s dismissal of Trémaux is motivated by concern that others might think punctuated equilibrium theory was tainted by a connection with Trémaux. (shrink)

_Investigates the philosophical relationship between Levinas and Heidegger in a nonpolemical context, engaging some of philosophy’s most pressing issues._.

We must agree, I think, with Frank Ebersole that there is something preposterous in supposing that the God of religious belief, the God who handed down tablets to Moses on Mt. Sinai, etc., should be proven to exist by the ontological argument. Indeed, when we place the one, the ontological argument, by the side of the other, the God of religious belief, there seems hardly to be any connection between them. But if we agree to this perception of things, what (...) sense can we make of the ontological argument, for example, the “pull” that it sometimes exerts on us? (shrink)

In order to by-pass immaterial historical bickering I shall stipulatively mean by ‘Radical Millianism’ just this much more than what Katz in his recent article in The Philosophical Review , ‘Names without Bearers’ , means by the unqualified term, ‘Millianism’; namely, whereas Katz means by ‘Millianism’ that theory of proper names which holds that proper names ‘have no linguistic meaning,’.

In the United Nations' Universal Declaration of Human Rights a quite large number of things are said to be ‘human rights’ and though in that Declaration the term ‘inalienable’ is not used to describe the rights in question it has been so used by commentators—at least with respect to some of the rights enumerated. I shall forgo asking the prior question as to whether any such thing as a human right exists and ask simply whether any such thing as an (...) inalienable right exists. My intention will be to show that it does not. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Hume's Missing Shade of Blue Re-viewed John 0. Nelson It is obviously important for Hume's purposes in the Treatise to maintain that simple ideas are always founded in precedent, resembling impressions;1 andhe explicitly, overandover, doesso, evensometimes being so carried away by this first principle ofhis science of man (T 7) or so careless as to say that not just all simple ideas but all ideas are founded (...) in precedent, resembling impressions. At the same time, as often noted, Hume explicitly maintains that it is possible for there to be a simple idea having no precedent, corresponding impression. He argues: There is however one contradictory phaenomenon, which may prove, that 'tis not absolutely impossible for ideas to go before their correspondent impressions... Suppose... a person to have enjoyed his sight for thirty years, and to have become perfectly well acquainted with colours of all kinds, excepting one particular shade of blue... Let all the different shades of that colour, except that single one, beplac'd before him... Now Iask, whether 'tis possible for him, from his own imagination, to supply this deficiency, and raise up to himselfthe idea ofthat particular shade, tho' it had never been conveyed to him by his senses? I believe there arefew but will be ofopinion that he can; and this may serve as a proof, that the simple ideas are not always derived from the correspondent impressions. (T 5) Nowjust prior to this concession (as Cummins calls it ), Hume has said that the full examination ofthis question [the causal relationship between ideas and impression] is the subject of the present treatise; and therefore we shall here content ourselves with establishing one general proposition, That all our simple ideas in their first appearance are deriv'd from simple impressions, which are correspondent to them, and which they exactly represent. (T 4) Volume XV Number 2 353 JOHN O. NELSON And just after the same concession, that a simple idea may be raised up which does not have a prior, correspondent impression, Hume says that it still remains true, that all our simple ideas proceed either mediately or immediately, from their correspondent impressions (T 7). Thus we have Hume explicitly asserting, it seems, both that all simple ideas have precedent correspondent impressions and that they do not. But this, on the face ofit, is an arrant contradiction! Can Hume have Homerically nodded? We have been quoting from the Treatise, but Hume makes the very same contradictory-seeming claims in the Enquiryl A thinker of Hume's acumen might nod for a page or two's quarter hour but not for all of nine years! Moreover, in both places Hume refers to the phenomenon of the impression-less idea ofblue as a contradictory phenomenon, indicating clearly enough that he was himself aware of there seeming to be an inconsistency here in his contentions. What can possibly be going on? Is Hume deliberately being paradoxical? Perhaps trying, for sensation's sake, to shock the reader and so increase sales of his work, as some commentators in the past might have wished to say? But this would be at the expense ofhis own contentions and principles and not the reader's, and not even Hume's bitterest foes and most malicious critics — so far as I know — have ever proposed that Hume would, figuratively speaking, like Oedipus, gouge out his own eyes, even in order to increase sales of the Treatise, nor does it make the slightest sense to think he would. The mystery deepens when we remember that Hume has said, in defining the program of the Treatise, that his intention is to establish the one general proposition that all our simple ideas in their first appearance are deriv'd from simple impressions, which are correspondentto them (T4). What astrange way, we want to exclaim, to show that all our simple ideas are derived from correspondent simple impressions by almost immediately afterwards arguing that it is possible to have an idea that has had no correspondent, precedent impression! Such an egregious nonsequitur mightbe expected ofan absolutely incompetent beginner in philosophy, but we are speaking of David Hume, generally recognized as the profoundest and most acute of... (shrink)

In response to a growing perception that America's youth lack the necessary values to grow and develop into adulthood in a socially healthy manner, character education has emerged as a rapidly growing proactive approach that serves to develop good character among young people. The authors examine several of the virtues thought to underlie good character from Character Counts!, a popular character education program, and emphasize the cultural complexities involved when promoting character education in a pluralistic society. 2012 APA, all rights (...) reserved). (shrink)

Russell said that physics drove him to a position not unlike that of Berkeley —by which he meant subjectivism or solipsism. ‘As regards metaphysics’, he tells us in hisAutobiography, ‘when, under the influence of Moore, I first threw off the belief in German idealism, I experienced the delight of believing that the sensible world is real. Bit by bit, chiefly under the influence of physics, this delight has faded, and I have been driven to a position not unlike that of (...) Berkeley, without his God and his Anglican complacency’. (shrink)

Pre-analytically at least some of our inductions seem to be possessed of rational justification. This comment would apply, for instance, to my present induction, ‘If that climber high on the Flatirons falls he will be killed,’ not to mention such more momentous inductions as, ‘If a full-scale nuclear war breaks out there will be greater destruction than in World War II.’ Notoriously, however, a few Humean reflections seem to strip even the most plausible of our inductions of all possible rational (...) justification, leaving them mere bare psychological faits accomplis: in effect, section V of the Enquiry's ‘Sceptical Solution of these Doubts.’. (shrink)

The limited objectives of this paper are to show that A), what seem to be merely superficial incoherencies in Rorty’s preferred pragmatism [according to which, “the only constraints on inquiry are conversational ones”] really are not but B), along with every assertion of Rorty’s defining his system and its consequences, belie an intrinsic incoherency resulting from that system’s intended conflation of “correspondence truth” and “pragmatic truth.” Then C), I shall argue that should we ask of a philosophy that denies to (...) its own statements of purported fact correspondence truth what use it is, the answer has to be, “Worse than no use at all”---at least, if like Rorty’s preferred pragmatism it demonstrably concludes in the conceptual annihilation of all inquiry. (shrink)

U.S. federal research funding is generally justified by promises of public benefits, but the specific natures and distribution of such benefits often remain vague and ambiguous. Furthermore, the metrics by which outcomes are reported often do not necessarily or strongly imply the achievement of public benefits. These ambiguities and discontinuities make it difficult to assess the public outcomes of federal research programs. This study maps the terms in which the purposes and the outcomes of Advanced Research Projects Agency-Energy -a relatively (...) young and innovatively structured federal research agency-have been discussed and reported. I find that ARPA-E’s creation and funding have been justified with reference to a broad repertoire of economic, environmental, and national security values, but that the agency has been evaluated only through intermediate scientific and economic metrics and study of internal organizational structure. I suggest that these means of assessment elide ARPA-E’s lack of the financial scale, long time horizon, built-in customer, and radical vision which have been historically important to high-impact federal innovation, and I recommend the tracking of metrics more directly related to ARPA-E’s public value purposes as the agency grows older. This discussion illustrates the inadequacy of currently widespread metrics and conventional wisdom for the design and assessment of societally relevant research. (shrink)

NATURES AND FUTURES FOR POLITICAL THEORY John S. Nelson What are the problematics, histories, forms, aims, conditions, methods, and topics proper to political theory? Plainly, these change from one context to another; and yet they may ...

Let me first explain what I am not attacking in this paper. I am not attacking, for instance, the right of free speech or any of the other specific rights listed in the U.S. Constitution's Bill of Rights or the United Nations' Charter. I am, rather, attacking any specific right's being called a ‘human right’. I mean to show that any such designation is not only fraudulent but, in case anyone might want to say that there can be noble lies, (...) grossly wicked, amounting indeed to genocide. (shrink)

The author argues that, Although zeno's paradoxes on motion cannot be resolved in their own terms, They are nonetheless illegitimate. Examining the paradox of achilles and the tortoise, He finds that the mechanism of zeno's argument consists in an equivocal concept of motion characterized at once by a constant rate and by proportionate segments of movement. He then contends it is illegitimate to treat the concept of motion and its subconcepts like the postulates of a deductive system. However, That the (...) common theory of meaning presupposed by zeno's paradoxes is erroneous would have to be demonstrated metaphysically. (staff). (shrink)

Studies the context of Giordano Bruni's Eroici furori in the light of two traditional literary forms; prose commentaries on verses, and Platonic love treatises.